Can you take claritin with mucinex dm

Taking Claritin with alcohol can cause dizziness, drowsiness and increased risk for overdose, states RxList. According to MedlinePlus, signs of Claritin overdose include excessive ...

Can you take claritin with mucinex dm. If you are taking doxycycline and experiencing stomach discomfort in your stomach or diarrhea, talk to your healthcare provider or pharmacist. They can recommend safe alternative options to Pepto-Bismol. 6. Iron supplements. If you have low iron levels, your healthcare provider may recommend an iron supplement. Iron supplements are available as ...

Claritin is an antihistamine and Sudafed is a decongestant. They are both used to treat allergy and hayfever symptoms such as runny nose. However, Claritin is also used to treat allergic skin reactions such as such as hives and itching in people with chronic skin reactions, whereas Sudafed is used to treat nasal and sinus congestion.

A doctor has provided 1 answer. Yes: These medications can be taken together because each has a different mode of action. Mucinex (guaifenesin) is prescribed to loosen the mucus. Claritin-d is an antihistamine and a decongestant. So the two of the drugs together should 1.) loosen the secretions, 2.) Claritin should decrease any allergic ...Although these drugs are safe to take on their own, there is a potential for drug interactions when they are taken together. The most common side effect of taking mucinex and zyrtec together is drowsiness. This is because both drugs can cause drowsiness as a side effect. When taken together, the drowsiness may be magnified.Do you take Mucinex dm and Cefdinir? Personalize this study to your gender and age. On Feb, 17, 2024. 14 people who take Mucinex dm and Cefdinir together, and have interactions are studied. What is Mucinex dm? Mucinex dm has active ingredients of dextromethorphan hydrobromide; guaifenesin. It is used in cough.Ask your question. Meet your new favorite doctor. yes: They both do different things. Mucinex (guaifenesin) is an expectorant for helping to loosed mucus. Clariten d is an antihistamine an.NSAIDs can increase blood pressure and overall cardiovascular risk. When it comes to Mucinex (guaifenesin), an OTC expectorant that helps to thin and loosen mucous secretions, you are pretty safe when it comes to dangerous interactions. Unlike many over-the-counter drugs, Mucinex has very few reported drug interactions and none are reported ...Descriptions. Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Answer. Thanks for reaching out! Benzonatate (generic for Tessalon) can safely be taken with most other cough medications. It should be noted however, that for most cough medications, there is a lack of evidence available showing that using a combination is more effective than using one alone.But taking meds like antihistamines can lead to a new problem: You feel like your mouth could double as the Sahara Desert. Before you go pointing fingers at your pill cabinet, however, please take note: it isn't Mucinex that dehydrates you. Nor is it Mucinex-D, Mucinex-DM or any other decongestant containing the active ingredient guaifenesin.• Check this list before taking any over the counter medicine and take it as directed on the package • (just make sure the You may use the store-brand product instead of the brand names listed below active ingredients list on the box matches) • This list does not include every over the counter product.Specializes in. Claritin d combines an antihistamine (loratadine) with a decongestant (pseudo-ephedrine). Mucinex (guaifenesin) is an expectorant. These are safe to take together. Would make sure that Mucinex product is plain Mucinex and not mucinex-d (which also contains pseudo-ephedrine) before taking these together. Answered Jan 1, 2020.Xarelto disease interactions. There are 6 disease interactions with Xarelto (rivaroxaban) which include: bleeding. valvular heart disease. antiphospholipid syndrome. hepatic impairment. renal disease. unstable blood pressure.

Yes, Mucinex and Nyquil can be taken together because they contain different ingredients, but Mucinex DM and Nyquil should not be taken together because they share a common ingredient, dextromethorphan. Instead of taking Mucinex DM and Nyquil together you should just take Nyquil. Mucinex contains guaifenesin which is an …Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency. Yes: Claritin is an antihistamine and will dry up mucous. Mucinex (guaifenesin) dm is a mucous thinner (guiafenisin) and a non-narcotic coug.dextromethorphan food. Applies to: Mucinex Children's Multi-Symptom Cold & Fever (acetaminophen / dextromethorphan / guaifenesin / phenylephrine) Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment.The active ingredients in Mucinex DM are guaifenesin 1200 milligrams and dextromethorphan HBr 60 milligrams. Mucinex DM is an expectorant and cough suppressant. According to WebMD....Drug interactions are reported among people who take Mucinex dm and Amoxicillin. Common interactions include neck pain among females, and pruritus among males. The phase IV clinical study analyzes what interactions people have when they take Mucinex dm and Amoxicillin together. It is created by eHealthMe based on 64 reports from the FDA, and is ...There is no known drug interaction between azithromycin and Mucinex (guaifenesin). They are considered safe to take together. In fact, Mucinex can be a great medication choice to help clear up the symptoms you are experiencing (chest congestion, excess mucus etc.,). While azithromycin is a commonly used antibiotic for a number of …

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Yes, you can take Claritin and Mucinex DM together. The two medications work in different ways and do not interact with each other.Yes, you can take Claritin and Mucinex DM together. The two medications work in different ways and do not interact with each other.clonazePAM dextromethorphan. Applies to: clonazepam and Mucinex DM (dextromethorphan / guaifenesin) Using clonazePAM together with dextromethorphan may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor ...empty entire contents of packet onto tongue and swallow. for best taste, do not chew granules. do not take more than 6 doses in any 24-hour period. Age. Dose. adults and children 12 years and over. 2 to 4 packets every 4 hours. children 6 years to under 12 years. 1 to 2 packets every 4 hours. dextromethorphan melatonin. Applies to: Mucinex DM (dextromethorphan / guaifenesin) and melatonin. Using dextromethorphan together with melatonin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor ... Summary: Drug interactions are reported among people who take Claritin and Robitussin. Common interactions among females include pollakiuria and therapeutic response unexpected. Common interactions among males include pneumonia and emotional distress. The phase IV clinical study analyzes what interactions people have when they take Claritin and ...

So amoxicillin for ear and throat, two shots of I don’t know what in the backside, Mucinex for the thick nasty phlegm, and Flonase, Claritin, and Zyrtec to alternate. Best thing—- the cough is finally actually bringing the stuff up about 6 hours after taking a 12-hour Mucinex. Aug 29, 2022 · Antihistamines are considered safe to use. They are used for a wide range of symptoms including post nasal drip, congestion, and allergy symptoms. Claritin, Zyrtec, and Allegra all last 24 hours and are good options to combine with Wellbutrin if needed. While most antihistamines are considered safe with Wellbutrin, one exception may be Benadryl. Claritin is in the drug class antihistamines. Claritin is used to treat the following conditions: Allergic Rhinitis; Urticaria; Mucinex Sinus-Max Clear & Cool. A total of 51 drugs are known to interact with Mucinex Sinus-Max Clear & Cool. Mucinex sinus-max clear & cool is in the drug class nasal antihistamines and decongestants. Yes, you can take Zyrtec and Mucinex together and it is absolutely safe to do so. Zyrtec is Cetirizine, a second-generation antihistamine which is used to treat a variety of allergy symptoms (1). Mucinex, on the other hand, is Guaifenesin, an expectorant. Guaifenesin loosens up the thick mucus blocking your airways and helps it get removed.If you are taking doxycycline and experiencing stomach discomfort in your stomach or diarrhea, talk to your healthcare provider or pharmacist. They can recommend safe alternative options to Pepto-Bismol. 6. Iron supplements. If you have low iron levels, your healthcare provider may recommend an iron supplement. Iron supplements are available as ...Key takeaways: Gabapentin (Neurontin) can interact with medications and substances that make you sleepy. These include opioids, benzodiazepines, and alcohol. Gabapentin can interact with some over-the-counter (OTC) medications and supplements. These include antihistamines as well as products that contain magnesium or aluminum.Can i take mucinex dm with metoprolol tartarte? 2 doctors weighed in across 2 answers. can i take claritin d24 and mucinex dm together? i took claritin d24 at around 11:30pm last night and i want to take mucinex dm now around 9am is that okay?: : …In general, you don't want to combine Dimetapp and Claritin on a consistent basis since both of them contain an antihistamine. If you take both together, you are essentially 'double dosing' on antihistamines. It's important to note that there are several different Dimetapp products on the market, and they all have different ingredients.dextromethorphan food. Applies to: dextromethorphan. Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with dextromethorphan.

It is based on dextromethorphan hydrobromide; guaifenesin and hydroxyzine hydrochloride (the active ingredients of Mucinex dm and Hydroxyzine hydrochloride, respectively), and Mucinex dm and Hydroxyzine hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

Twitter has introduced a new feature that lets users choose almost any emoji to react to a direct message in a thread. Twitter has introduced a new feature that lets users choose a...pounding heartbeats or fluttering in your chest; or. severe dizziness, nervousness, or restless feeling. Common Claritin-D side effects may include: dry mouth, nose, or throat; mild dizziness; or. sleep problems ( insomnia ). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.Ask your doctor before taking ibuprofen if you take any of the following, as there can be adverse reactions when the two medications mix: Anticoagulants, or blood thinners, like Coumadin and ...Aleve-D Sinus & Cold Interactions. There are 567 drugs known to interact with Aleve-D Sinus & Cold (naproxen/pseudoephedrine), along with 19 disease interactions, and 5 alcohol/food interactions. Of the total drug interactions, 110 are major, 436 are moderate, and 21 are minor.I understand that you can take Mucinex and TheraFlu together - but not if you're taking blood. Pressure medicine. ... Can theraflu and mucinex dm be taken together I have a sore. 7.15.2019. Dr Su S. Doctor. 26,240 Satisfied Customers. I have Walking pneumonia. Dr. gave me prednisone 20 mg, 6.3.2019. Dextromethorphan; Guaifenesin Oral Solution. Dextromethorphan and guaifenesin come combined in some medications to treat cold and flu symptoms. Dextromethorphan is a cough suppressant. Guaifenesin is an expectorant that thins mucus to ease chest congestion. A healthcare provider can tell you if this medication is safe and likely to help you. They cause me intolerable fatigue and painful nose dryness with nosebleeds. While rinsing my nose helps, I have had the most success taking Mucinex for post-nasal drip, my most bothersome symptom. It seems to break up the thick mucus and allow me to breathe, swallow, and sleep. Yet studies and many doctors claim Mucinex doesn't work any ...Answer. Thanks for reaching out to us! Yes, Zyrtec-D (cetirizine; pseudoephedrine) can safely be taken with Mucinex (guaifenesin). There is no drug interaction between them. All three of the drugs that are contained in these two products are in different drug classes and work in different ways to treat cough/cold symptoms.Mucinex for Bronchitis User Reviews (Page 2) Mucinex has an average rating of 5.9 out of 10 from a total of 50 reviews for the treatment of Bronchitis. 50% of reviewers reported a positive experience, while 40% reported a negative experience.

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Mucinex is the brand name for several over-the-counter drugs that treat allergy, cold, and flu symptoms.Almost all Mucinex products contain guaifenesin, a medication that loosens or thins mucus to make it easier to clear from airways.. Many people take Mucinex to relieve chest or sinus congestion. Other Mucinex products contain a combination of medications that treat cough, sinus pressure ...To prevent chapped hands: To prevent chapped hands: To soothe chapped and sore hands: Hands - chapped and dry Dinulos JGH. Eczema and hand dermatitis. In: Dinulos JGH, ed. Habif's ...When you post on Twitter, every user that follows your Twitter account can see the message. Alternatively, direct messages on the site are private messages between two users that n...Applies to: Xanax (alprazolam) and Mucinex Fast-Max DM Max (dextromethorphan / guaifenesin) Using ALPRAZolam together with dextromethorphan may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor ...Mucinex®, Robitussin® (plain) Combination products with dextromethorphan are also allowed: Robitussin DM®, Tab Tussin DM™, Coricidin HBP Chest Congestion and Cough® , Equate Tussin DM® X AVOID decongestants like pseudoephedrine (Sudafed®) or phenylephrine (Sudafed PE®) Constipation Docusate, Senna, Psyllium, Bisacodyl, Polyethylene glycolAnswer. Yes, antihistamines and mucus relief products (e.g. expectoranst such as Mucinex) are safe to take together. They are often beneficial to combine as they can work synergistically together. Antihistamines can help to dry mucus secretions and prevent post-nasal drip. Expectorants thin secretions and reduce their adhesiveness in the ...Benadryl - Klonopin Interaction. Use of Klonopin and Benadryl together could potentially cause additive side effects, such as: Sedation. Dizziness. Central nervous system depression. Respiratory depression. Confusion. Due to the increased risk of side effects, they should be used together with caution, and you certainly should not operate heavy ...Call your doctor or 911 if you think you may have a medical emergency. SOC 2 Type 2Certified. mucinex (guaifenesin) dm vs. robitussin dm? i've got a very bad, "dry" cough and lots of "wheezing" the robitussin has done nothing! should i try the mucinex (guaifenesin)?: Yes, except: Be very sure to drink lots and lots of water - both when. ….

Aug 29, 2022 · Antihistamines are considered safe to use. They are used for a wide range of symptoms including post nasal drip, congestion, and allergy symptoms. Claritin, Zyrtec, and Allegra all last 24 hours and are good options to combine with Wellbutrin if needed. While most antihistamines are considered safe with Wellbutrin, one exception may be Benadryl. dextromethorphan food. Applies to: Mucinex DM (dextromethorphan / guaifenesin) Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated ...The cough suppressant (dextromethorphan) relieves the intensity and frequency of coughs. Standard Mucinex DM dosage for wet or dry cough: 600/30–1200/60 mg (one to two regular-strength tablets or one maximum strength tablet) every 12 hours. Maximum Mucinex DM dosage for wet or dry cough: 1200/60 mg (two regular-strength tablets or one maximum ...dextromethorphan cyclobenzaprine. Applies to: Mucinex DM Maximum Strength (dextromethorphan / guaifenesin) and cyclobenzaprine. Using dextromethorphan together with cyclobenzaprine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme ...Medications: You do not have to worry, you can take all 3, but if your using Mucinex (guaifenesin) to treat mucus from asthma you need to see an allergist, get tested to determine your triggers and control your asthma better.LORazepam dextromethorphan. Applies to: lorazepam and Mucinex DM (dextromethorphan / guaifenesin) Using LORazepam together with dextromethorphan may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, …Drug interactions are reported among people who take Claritin-d and Mucinex. Common interactions among females include injection site pain and injury. Common interactions among males include bronchitis and abdominal pain. The phase IV clinical study analyzes what interactions people have when they take Claritin-d and Mucinex together.pounding heartbeats or fluttering in your chest; or. severe dizziness, nervousness, or restless feeling. Common Claritin-D side effects may include: dry mouth, nose, or throat; mild dizziness; or. sleep problems ( insomnia ). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Can you take claritin with mucinex dm, DMAIC Model - The DMAIC model is commonly used in the Six Sigma process. Learn the ins and outs of the DMAIC model and how it applies to business optimization. Advertisement Proce..., Excessive dosages or long-term dosing of Mucinex has been linked with nausea, diarrhea, headache, and kidney stones, but these appear to occur only rarely. There are very few published case reports documenting Mucinex overdoses being a contributing factor to serious side effects or death. Animal studies report an LD50 (lethal dose in 50% of a ..., Aug 28, 2017 · Medications: You do not have to worry, you can take all 3, but if your using Mucinex (guaifenesin) to treat mucus from asthma you need to see an allergist, get tested to determine your triggers and control your asthma better. , More about Mucinex ( guaifenesin ) Ratings & Reviews. Advil Cold and Sinus has an average rating of 7.5 out of 10 from a total of 30 ratings on Drugs.com. 72% of reviewers reported a positive effect, while 24% reported a negative effect. Mucinex has an average rating of 6.1 out of 10 from a total of 152 ratings on Drugs.com. 54% of reviewers ..., Can You Take Sudafed With Mucinex? Sudafed and Mucinex are two of the most popular OTC remedies for colds and coughs, and, yes, you can take them together …, Yes, there are 4 Mucinex over-the-counter (OTC) daytime products that can help with your sore throat. Three products come as lozenges that contain hexylresorcinol and one is an oral spray with benzocaine. They all belong to the Mucinex InstaSoothe line of products. Mucinex InstaSoothe Sore Throat + Cough Relief lozenges., dextromethorphan food. Applies to: Mucinex DM Maximum Strength (dextromethorphan / guaifenesin) Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of …, do not crush, chew, or break tablet. take with a full glass of water. this product can be administered without regard for timing of meals. adults and children 12 years and older: 1 tablet every 12 hours; not more than 2 tablets in 24 hours. children under 12 years of age: do not use., Summary: Drug interactions are reported among people who take Claritin and Robitussin. Common interactions among females include pollakiuria and therapeutic response unexpected. Common interactions among males include pneumonia and emotional distress. The phase IV clinical study analyzes what interactions people have when they take Claritin and ..., levocetirizine food. Applies to: levocetirizine. Alcohol can increase the nervous system side effects of levocetirizine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with levocetirizine., In general, you don't want to combine Dimetapp and Claritin on a consistent basis since both of them contain an antihistamine. If you take both together, you are essentially 'double dosing' on antihistamines. It's important to note that there are several different Dimetapp products on the market, and they all have different ingredients., Antihistamines. Antihistamines can be safely taken with a Prescription as they don’t really interact with one another. Common antihistamines include Benadryl, Claritin, Allegra, Zyrtec etc. Nasal decongestants. Nasal decongestants like Pseudoephedrine and Phenylephrine can be used along with Prednisone. However, the …, pseudoephedrine food. Applies to: Sudafed 12-Hour (pseudoephedrine) Consumer information for this interaction is not currently available. MONITOR: Coadministration of two or more sympathomimetic agents may increase the risk of adverse effects such as nervousness, irritability, and increased heart rate. Central nervous system (CNS) stimulants ..., Applies to: Mucinex DM (dextromethorphan / guaifenesin) Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with …, Medications: You do not have to worry, you can take all 3, but if your using Mucinex (guaifenesin) to treat mucus from asthma you need to see an allergist, get tested to determine your triggers and control your asthma better., Can You Take Claritin D and Mucinex Together. When it comes to managing allergies and congestion, many people wonder if it’s safe to take Claritin-D and Mucinex together. Claritin-D is a combination of an antihistamine and decongestant, which helps relieve allergy symptoms such as sneezing, itching, and nasal congestion. , Get free real-time information on USD/BTX quotes including USD/BTX live chart. Gainers Digital Media Solutions, Inc. (NYSE: DMS) jumped 78.8% to close at $2.11. Digital Media Solut..., Trazodone is a medication used to treat depression, while Mucinex is an over-the-counter medication used to relieve symptoms of the common cold. In general, it's safe to take Trazodone and Mucinex together, but both medications can cause drowsiness and other side effects. Be sure to talk to your doctor if you have any questions or concerns ..., If you are taking doxycycline and experiencing stomach discomfort in your stomach or diarrhea, talk to your healthcare provider or pharmacist. They can recommend safe alternative options to Pepto-Bismol. 6. Iron supplements. If you have low iron levels, your healthcare provider may recommend an iron supplement. Iron supplements are available as ..., Mucinex (guaifenesin) and Sudafed (pseudoephedrine) can safely be taken together. In fact, there are a variety of medications that combine both active ingredients. These two meds are used to treat ..., How to use Mucinex Sinus-Max Severe Congestion (DM) 5 Mg-10 Mg-325 Mg-200 Mg Cap See also Warning section. If you are using the over-the-counter product, read and follow all directions on the ..., Can you take musinex and claritin (loratadine) d at the same time? Yes: Mucinex (guaifenesin) is an expectorant - it helps thin out the mucus. Claritin D has both an anti-histamine (dry out the mucus) and a decongestant - help get the mucus out. Yes: Mucinex (guaifenesin) is an expectorant - it helps thin out the mucus., Applies to: Mucinex DM (dextromethorphan / guaifenesin) Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with dextromethorphan., 2 doctors weighed in across 2 answers. can i take sudafed and mucinex sinus max together? the sudafed has pseudoephedrine mucinex sinus max has phenylephrine. thanks in advance!: Steam inhalation: Neither of these medications is likely to do you muc., dextromethorphan food. Applies to: Mucinex DM (dextromethorphan / guaifenesin) Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated ..., Yes, you can take Claritin and Mucinex DM together. The two medications work in different ways and do not interact with each other., But their active ingredients and uses vary. It's usually safe to take Mucinex with Nyquil or Dayquil. But you should avoid taking Nyquil or Dayquil with Mucinex DM, since they all contain dextromethorphan. It's possible to take too much acetaminophen if you combine Tylenol with Nyquil or Dayquil. Talk to your healthcare provider or ..., The phase IV clinical study analyzes what interactions people who take Carvedilol and Mucinex have. It is created by eHealthMe based on reports of 626 people who take Carvedilol and Mucinex from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions., Mucinex DM contains two active ingredients, guaifenesin and dextromethorphan, and the length of time these substances remain in your system can vary depending on several factors, including your metabolism, liver and kidney function, and the dosage you take. Guaifenesin typically has an elimination half-life of approximately 1 to 3 hours, which ..., Applies to: alprazolam and Mucinex DM (dextromethorphan / guaifenesin) Using ALPRAZolam together with dextromethorphan may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination., Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency. Yes: Claritin is an antihistamine and will dry up mucous. Mucinex (guaifenesin) dm is a mucous thinner (guiafenisin) and a non-narcotic coug., Common interactions among females include embolism arterial and muscle spasms. Common interactions among males include weight decreased and dyspnoea. The phase IV clinical study analyzes what interactions people have when they take Mucinex dm and Imodium together. It is created by eHealthMe based on data from the FDA, and is updated regularly., Answer. Hello and thanks for reaching out! More than happy to answer your question. Yes, Zyrtec (cetirizine) and Mucinex (guaifenesin) may be taken together as there is no drug interaction between the two. In fact, both products are included in many different cough/cold formulas and have a synergistic effect when used together.